Sr. Director, T Cell Immunology, Infectious Disease at ModernaTX, Inc. in Cambridge, Massachusetts

Posted in Other 15 days ago.





Job Description:

The Role:



The Infectious Disease team at Moderna is looking for a highly enthusiastic and talented immunologist with expertise in T cell immunology, cellular phenotyping, mucosal immunology, and epitope mapping. Additional experience in imaging, clonal repertoire analysis, single cell sequencing, antigen design, T cell development, cytotoxic mechanisms, tolerance, Th skewing, and exhaustion/reversal would be of great additional interest. The individual will oversee a dynamic team of cellular immunologists at all levels aimed at understanding the current potential of the platform to leverage cellular immunity as well as to develop a robust program to explore future opportunities to fully harness the power of the cellular immune response. The individual will incorporate and develop state of the art, cutting edge technological strategies to expand our understanding and opportunity to tune T cell help, drive cytotoxicity, explore non-canonical T cell functions, shape cellular immune interactions and program antigen-presentation. The individual will work with a team of virologists, microbiologists, biochemists, computational biologists, immunologists to shape the host: pathogen interaction to improve mRNA therapeutic strategies. The ability to effectively communicate across internal multi-disciplinary teams and with external partners is required. Applicants should be outstanding scientists, have already led teams of immunologists, possess collaborative team spirit, be an excellent communicator, and should be excited to work with cutting edge mRNA technology in the advancement of vaccines and therapeutics against infectious disease threats.



Here's What You'll Do:



  • Lead a team of immunologists focused on exploring the role of mRNA/LNP vaccine programming of cellular immunity.


  • Develop novel technologies to explore the role of T cell responses in vaccine mediated protective immunity.


  • Develop new approaches to wholistically evaluate the cellular immune response following vaccination to understand the impact and opportunities to shape the cellular immune response.


  • Drive strong collaborative efforts to support mRNA vaccine and therapeutic virology and bacteriology programs.


  • Drive technological collaborations and support for other therapeutic areas.


  • Shepherd the development of automated pipelines and immune assays to support cellular immune investigation across therapeutic areas.


  • Bring a passion for cellular immunology and novel-cutting edge tools to drive enhanced surveillance, control, and clearance of disease.


  • Drive the development and optimization of preclinical models for the evaluation of novel therapeutic strategies.


  • Inspire the incorporation of novel sequencing, imaging, and proteomic tools to understand and exploit cellular immune activity.


  • Support and execute experiments within a cross-functional team.


  • Effectively communicate project goals, timelines, progress, and results across functional groups


  • Interpret, summarize, and present experimental data and results at group meetings, project meetings, and department meeting.





Here's What You'll Bring to the Table:



  • PhD or equivalent with 10-15 years' experience or equivalent industry experience


  • Solid immunology background, with experience in flow cytometry, single cell sequencing, and multi-OMIC analysis


  • Ability to think critically and demonstrate troubleshooting and problem-solving skills


  • Strong written and oral communication skills


  • Ability to interact effectively with all levels of personnel within the organization


  • Candidate will be curious in exploring new paths for drug discovery, bold in proposing creative experimental designs and ideas. Will work collaboratively with multifunctional teams and will be relentless in pursuing successful outcomes





Moderna is pleased to provide you and your family with a comprehensive and innovative suite of benefits, including:



  • Highly competitive and inclusive medical, dental and vision coverage options

  • Flexible Spending Accounts for medical expenses and dependent care expenses

  • Lifestyle Spending Account funds to help you engage in personal enrichment and self-care activities

  • Family care benefits, including subsidized back-up care options and on-demand tutoring

  • Free premium access to fitness, nutrition, and mindfulness classes

  • Exclusive preferred pricing on Peloton fitness equipment

  • Adoption and family-planning benefits

  • Dedicated care coordination support for our LGBTQ+ community

  • Generous paid time off, including:
    • Vacation, sick time and holidays
    • Volunteer time to participate within your community
    • Discretionary year-end shutdown
    • Paid sabbatical after 5 years; every 3 years thereafter

  • Generous Paid Leave offerings, including 18 weeks of 100% paid parental leave for all new parents

  • 401k match and Financial Planning tools

  • Moderna-paid Life, LTD and STD insurance coverages, as well as voluntary benefit options

  • Complimentary concierge service including home services research, travel booking, and entertainment requests

  • Free parking or subsidized commuter passes

  • Location-specific perks and extras!




About Moderna



Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world.


By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities.


We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S.


As we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute and make a meaningful impact.


If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.


Moderna is a smoke-free, alcohol-free and drug-free work environment.


Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply!


Moderna is proud to be an equal opportunity workplace and is an affirmative action employer.


Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. Moderna is an E-Verify Employer in the United States. We also consider qualified applicants regardless of criminal histories, consistent with legal requirements.


Belonging, Inclusion, and Diversity are critical to the success of our company and our impact on society. We're focused on attracting, retaining, developing, and advancing our employees and believe that by cultivating diverse experiences, backgrounds, and ideas, we can provide an environment where every employee is able to contribute their best.


Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at leavesandaccommodations@modernatx.com. (EEO/AAP Employer)


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