Job Description:
The final salary or hourly wage, as applicable, paid to each candidate/applicant for this position is ultimately dependent on a variety of factors, including, but not limited to, the candidate's/applicant's qualifications, skills, and level of experience as well as the geographical location of the position.
Applicants must be legally authorized to work in the United States. Sponsorship not available.
Our client is seeking an Associate Scientist in Seattle, WA.
Role Description
Key Responsibilities:
• Design and execute nucleic acid ligation reactions using "splint ligation" methodology
• Design and execute ion-pairing (IP) reversed-phase (RP) chromatography methods
• Perform purification of oligonucleotides using chromatography and/or preparative PAGE
• Design and evaluate the performance of new biophysical assays to identify and assess CQA's
• Manage samples and data related to gene editing platform process development
• Provide experimental design and executional support to team members in adjacent and related functions (e.g. clinical development programs, high throughput process development, etc.)
• Actively participate and support lab maintenance and continuous improvement initiatives
• Maintain accurate and detailed laboratory notebook and documentation
• Summarize and present data in group meetings and contribute to group discussions
• Author technical reports, study memos, and protocols
Skills & Requirements
Basic Qualifications:
Top Skills: - Proficiency with biochemical techniques to analyze oligonucleotides (PAGE and CE) - Proficiency with analytical IP-RP chromatography for RNA (including mRNA) purity - Experience working with, storing, and analyzing purified nucleic acids and proteins - Experience with optimizing molecular cloning reactions - Experience with gene editing primary human cells or immortalized cell-lines Seeking a highly motivated Sr. Associate Scientist, or Scientist, to work in a fast-paced PD environment applying rigorous biochemical principles towards developing and characterizing ligated oligonucleotides for gene editing applications. As a part of the Gene Delivery and Editing Process Development (GDEPD) organization, the ideal candidate will possess sufficient experience with handling, manipulating, and characterizing in vitro produced RNA oligomers (50 - 200 nt). A successful scientist will directly employ molecular cloning, biophysical and analytical tools to develop our next-generation gene edited therapies through the development of RNA oligomers. An outstanding candidate will be driven by a desire to create, optimize, and define processes with speed in a collaborative environment.
• STEM degree with 2+ years of relevant industry experience; title/compensation will be commensurate with education, experience, and skillset
• Proficiency with biochemical techniques to analyze oligonucleotides (PAGE and CE)
• Proficiency with analytical IP-RP chromatography for RNA (including mRNA) purity
• Experience working with, storing, and analyzing purified nucleic acids and proteins
• Independently motivated with the ability to work in teams
• Ability to communicate clearly and concisely through oral presentation and technical writing
• Ability to leverage literature, internal and external resources to solve problems and develop new technologies
• Possess a growth mindset and the ability to thrive in a fast-paced, highly collaborative environment Preferred Qualifications:
• Degree in biological or chemical engineering, biochemistry, or bio-related field
• Experience with optimizing molecular cloning reactions
• Experience with gene editing primary human cells or immortalized cell-lines
• Experience with solid-phase oligonucleotide synthesis
• Experience with bioinformatic tools used to predict RNA secondary structure
Benefits/Other Compensation
This position is a contract/temporary role where Hays offers you the opportunity to enroll in full medical benefits, dental benefits, vision benefits, 401K and Life Insurance ($20,000 benefit).
Why Hays?
You will be working with a professional recruiter who has intimate knowledge of the industry and market trends. Your Hays recruiter will lead you through a thorough screening process in order to understand your skills, experience, needs, and drivers. You will also get support on resume writing, interview tips, and career planning, so when there's a position you really want, you're fully prepared to get it.
Nervous about an upcoming interview? Unsure how to write a new resume?
Visit the Hays Career Advice section to learn top tips to help you stand out from the crowd when job hunting.
Hays is committed to building a thriving culture of diversity that embraces people with different backgrounds, perspectives, and experiences. We believe that the more inclusive we are, the better we serve our candidates, clients, and employees. We are an equal employment opportunity employer, and we comply with all applicable laws prohibiting discrimination based on race, color, creed, sex (including pregnancy, sexual orientation, or gender identity), age, national origin or ancestry, physical or mental disability, veteran status, marital status, genetic information, HIV-positive status, as well as any other characteristic protected by federal, state, or local law. One of Hays' guiding principles is 'do the right thing'.
We also believe that actions speak louder than words.
In that regard, we train our staff on ensuring inclusivity throughout the entire recruitment process and counsel our clients on these principles. If you have any questions about Hays or any of our processes, please contact us.
In accordance with applicable federal, state, and local law protecting qualified individuals with known disabilities, Hays will attempt to reasonably accommodate those individuals unless doing so would create an undue hardship on the company. Any qualified applicant or consultant with a disability who requires an accommodation in order to perform the essential functions of the job should call or text 813.336.5570.
Drug testing may be required; please contact a recruiter for more information.
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#1164350 - Laurie McComb