Characterize CHO cell lines using molecular biology techniques, including qPCR, ddPCR, Southern blot, and northern blot
Sanger sequencing analysis
Design of primer/probe reagents for gene copy number analysis
Use of gel and blot imaging instruments
Maintain detailed, accurate, and clear documentation of experiments and activities
Effectively organize and communicate research progress and planned activities through oral and written presentations
Collaborate with colleagues in the Cell Line Development group and across multiple functional areas of the Bioprocess Development and Launch department to advance the company Biologics Pipeline
Maintain a high level of productivity in the lab
Demonstrate scientific initiative and creative thinking to achieve project goals and contribute team performance in a climate of scientific rigor
Contribute to the smooth and effective operation of the CHO Cell Line Development labs through the 5S program
Understand and adhere to corporate standards regarding code of conduct, safety, appropriate handling of materials, and GxP compliance
Qualifications:
Bachelor's Degree or Master's Degree in Cell/Molecular Biology or a related field with 5 years of relevant experience; pharmaceutical industry experience is preferred
Expertise in molecular biology techniques, including DNA/RNA extraction and quantification, PCR-based assays, gel electrophoresis, blotting techniques and sequencing analysis
Hands-on experience with mammalian cell culture
Experience with DNA sequence manipulation software and common software packages such as Microsoft Office
Excellent written and interpersonal communication skills with the ability to build strong relationships with peers and cross-functional team members
Strong planning, multitasking, time management, and troubleshooting skills
Collaborative and proactive attitude with strong scientific curiosity, work ethic, and attention to detail
Authorization to work in the United States is required
Preferred Qualifications:
Experience with expression vector elements, construction, and molecular cloning
Experience with digital PCR assays, such as droplet digital PCR (ddPCR)
Proven track record in vector biology, cell line genetic characterization, and/or CHO cell line development
EEO:
"Mindlance is an Equal Opportunity Employer and does not discriminate in employment on the basis of - Minority/Gender/Disability/Religion/LGBTQI/Age/Veterans."