Associate Scientist II, Downstream Process Development at Alexion in New Haven, Connecticut

Job Description:

This is what you will do:



The Associate Scientist II is responsible for performing assigned experimental tasks to support the development and optimization of manufacturing processes for Alexion's biotherapeutic candidates. The Associate Scientist II will work routinely in collaboration with other members of Biologics Process Development, Technology Transfer and Analytical Sciences, including all other groups in Product Development and Clinical Supply.



You will be responsible for:

• Conducting experimental studies to develop, optimize, and characterize manufacturing processes for biotherapeutic candidates


• Executing experimental studies to support scale up of manufacturing processes or troubleshooting of issues at manufacturing scale as required for therapeutic proteins


• Documenting study results in notebooks, forms, and technical reports


• Assisting in laboratory management including ordering and maintenance

You will need to have:

• BS (with 2+ years of experience) or MS degree in Biochemistry, Chemistry, Chemical Engineering, or related discipline from an accredited university with zero years of experience.


• Cross-functional critical thinking skills.


• Ability to effectively communicate scientific data in the form of presentations, experimental note booking, and authoring of technical documents.


• Demonstrated capacity to develop deeper understanding of technical topics via research and integrate knowledge into work processes.


• Capability to independently plan, execute and train peers on routine laboratory activities.


• The duties of this role are conducted in an lab environment. As is typical of a lab-based role, employees must be able, with or without an accommodation to: lift/carry 15/30 pounds unassisted/assisted; work comfortably in a controlled environment with and around biological, infectious, and hazardous materials; gown/degown PPE; use a computer; engage in communications via phone, video, and electronic messaging; engage in problem solving and non-linear thought, analysis, and dialogue; collaborate with others; maintain general availability during standard business hours.


• Proficiency with various MS Office programs, including Word, Excel, Outlook, and PowerPoint

We would prefer for you to have:

• Experience in any area of biologics process development (cell culture and/or purification)


• Experience performing chromatographic protein purification


• Experience with Unicorn programming and operation of AKTA and other chromatography skids


• Experience in nano filtration and ultrafiltration/diafiltration


• Experience with Statistical Design of Experiments Software (e.g., JMP)

Date Posted

09-Sep-2024



Closing Date

08-Dec-2024Alexion is proud to be an Equal Employment Opportunity and Affirmative Action employer. We are committed to fostering a culture of belonging where every single person can belong because of their uniqueness. The Company will not make decisions about employment, training, compensation, promotion, and other terms and conditions of employment based on race, color, religion, creed or lack thereof, sex, sexual orientation, age, ancestry, national origin, ethnicity, citizenship status, marital status, pregnancy, (including childbirth, breastfeeding, or related medical conditions), parental status (including adoption or surrogacy), military status, protected veteran status, disability, medical condition, gender identity or expression, genetic information, mental illness or other characteristics protected by law. Alexion provides reasonable accommodations to meet the needs of candidates and employees. To begin an interactive dialogue with Alexion regarding an accommodation, please contact accommodations@Alexion.com. Alexion participates in E-Verify.


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