Scientist, OTD Target Validation at AstraZeneca in Gaithersburg, Maryland

Job Description:

Scientist, OTD Target Validation



Gaithersburg, MD


AstraZeneca's vision in Oncology is to push the boundaries of science to change the practice of medicine, transform the lives of patients living with cancer, and to ultimately eliminate cancer as a cause of death. A broad pipeline of next-generation medicines is bringing novel concepts in oncology to address unmet medical need.



This Opportunity


We are seeking highly a motivated independent lab Scientist with wet-bench laboratory experience to join our Tumor Targeted Delivery team in Early Oncology in Gaithersburg, MD USA. As a Scientist, you will support target validation efforts for tumor-targeted therapies, such as antibody-drug-conjugates (ADCs) and targeted radio-conjugates. You will work collaboratively with cross-functional teams to advance pipeline programs and deepen our understanding of all aspects of target biology.



Main Duties and Responsibilities

• Support target validation efforts for one or more pipeline programs
  
  

• Support cross-functional teams and work collaboratively with project leads to ensure the timely generation and dissemination of critical program data
  
  

• Design, conduct, troubleshoot and analyze in vitro experiments using an array of biochemical, molecular and cellular biology techniques to validate new targets and dissect the mechanism of action of novel cancer therapeutics
  
  

• The ideal candidate will be highly collegial, collaborative, data-driven, and have a passion to learn and grow
  
  

Essential Requirements

• Bachelor's Degree in relevant discipline with 3+ years of laboratory research experience, or Master's Degree with 1+ years of laboratory research experience
  
  

• Solid understanding of cell and molecular biology
  
  

• Laboratory experience with mammalian cell culture and molecular and cell-based experimental techniques such as flow cytometry, western blots, qPCR, ELISA, confocal and fluorescent microscopy, cell cytotoxicity assays and CRISPR/Cas9 gene editing
  
  

• Works equally well independently with supervision and in collaboration with other teams
  
  

• Excellent written and verbal communication and interpersonal skills in a fast-paced matrix environment
  
  

• Ensures one's own work, and the work of peers, is compliant with Good Laboratory Practice, Safety, Health, and Environment standards and all other relevant internal AstraZeneca standards and external regulations
  
  

Desired Requirements

• Prior experience in the biopharmaceutical industry viewed favorably
  
  

• Experience in cancer research
  
  

About Our Gaithersburg Oncology Hub


Our Gaithersburg, Maryland facility creates life-changing medicines for people around the world. This campus employs more than 3,500 experts in our field and is only a short drive from Washington, DC. This modern and vibrant scientific campus is the home of R&D and Oncology in the US. Here, we play host to some of the most cutting-edge technology and lab spaces, all designed to inspire collaboration and cross-functional science. We are dedicated to creating a culture of inclusion and collaboration.


The Gaithersburg site offers a variety of amenities to help keep our employees happy and healthy. This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, dry cleaning, full-service cafeteria and copy center, game rooms, community garden and more. This is where you'll find newly-designed, activity-based work spaces to suit a variety of working styles while increasing collaboration between teams.



So, what's next?


Ready to make a difference? Apply now to join our team!


If you're curious to know more, please contact Bobbi Poole, our Talent Acquisition Partner.



Closing Date: October 14, 2024



Competitive remuneration and benefits apply


We offer a competitive Total Reward program including a market driven base salary, bonus and long term incentive. We have a generous paid time off program and a comprehensive benefits package.



Where can I find out more-



Our Social Media, Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/



Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/



Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en


AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We follow all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.


We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.


AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements. Apply Now