Scientist at AstraZeneca in Gaithersburg, Maryland

Job Description:

Scientist



Are you passionate about Science? Do you aspire to apply your expertise in a company that follows the science and turns ideas into life-changing medicines? If so, AstraZeneca is the place for you! We prioritize patients and strive to meet their unmet needs worldwide. We believe in being entrepreneurial, thinking big, and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you're our kind of person.



Accountabilities:

As a Scientist in our Analytical Sciences team in Gaithersburg, MD, you will support physicochemical analysis of biopharmaceutical products such as novel therapeutic proteins, monoclonal antibodies, antibody-drug conjugates, bispecific antibodies, etc. You will be involved in Chemistry, Manufacturing, and Controls (CMC) efforts, including analytical method development, method qualification/transfer, peak identification and structure elucidation, degradation pathway analysis, critical quality attributes (CQA) analysis, reference standard qualification, specification setting, comparability studies, release and stability testing. You will also serve as a subject matter expert for analytical separation methods.



Essential Skills/Experience:

- Bachelor's in biology, chemistry, or related field with 5+ years of experience
- Master's degree in biology, chemistry, or related field with 2+ years of experience
- In-depth knowledge in biochemical and biophysical analysis of proteins
- Strong background in chromatographic techniques such as SEC, RP-HPLC, HILIC, IEX, and HIC. Proficient with performing electrophoretic techniques such as SDS-PAGE, CE-SDS, CZE and iCE.
- Must be able to understand and apply moderately complex or advanced chemical concepts in a laboratory setting
- Ability to work in a highly matrixed structure and to interface and share ownership of projects with different groups within research and development
- Great teamwork and communication skills, both verbal and written
- Good multi-tasking, time management, and organizational skills
- The ability to follow SOPs, policies, and regulations, and to perform routine lab equipment maintenance.



Desirable Skills/Experience:

- Experience in operation of automated liquid handling equipment
- Familiarity with data analysis software such as Empower, OpenLab, BiopharmaFinder, ProteinMetrics, and Waters_Connect


At AstraZeneca's Biopharmaceuticals R&D division, we are always moving forward and searching for something new. Our supportive yet challenging approach makes for an inspiring learning environment. Every setback is seen as a chance to improve; every critique pushes us towards the next ground-breaking solution. We are courageous. We speak up, share opinions and make bold decisions that could change the course of patients' lives. We combine specialist knowledge with curiosity. Always searching for better ways of doing things and getting the best end-result. It takes a long-term mindset and resilience to work through challenges. We keep focused on business needs, pushing back when needed.



Join us today! Use our network to reach your potential. Join a community of highly qualified and motivated scientists. A place that's both supportive and challenging. There's continuous knowledge and information sharing, and we also constructively critique ourselves and the science. Join in and speak up to succeed.



AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.