We are seeking a highly talented and motivated Scientist I to join our Molecular Screening and Characterization group. The MSC group focuses on assay development, optimization, and execution of in vitro biochemical and cell based screens in collaboration with multiple therapeutic areas. The successful candidate will be responsible for executing robust in vitro screens (biochemical and cell-based) and delivering high quality data utilizing high-throughput mass spectrometry as well as common HTS tools. In this role, the Scientist will work closely with MSC and project team members to implement in vitro screening strategies as part of the overall project plan. The candidate should play an active role in communicating and collaborating with scientists across to advance projects through day to day interactions, presentation of data, and interpretation of results. The Scientist must be capable of working independently while contributing and participating in a team environment and must have excellent oral and written communication skills.
Qualification: • Master's degree in Chemistry, Analytical Chemistry, Biochemistry, Pharmacology, or related field with 0-2+ years of prior experience in a drug discovery laboratory setting working as part of a multi-disciplinary team • Bachelor's degree in Chemistry, Analytical Chemistry, Biochemistry, Pharmacology, or related field with 3-5+ years of prior experience in a drug discovery laboratory setting working as part of a multi-disciplinary team • Strong scientific foundation in the understanding and implementation of a wide range of biochemical and cell-based assays and readouts • Working knowledge of mass spectrometry • Able to think critically and creatively across multiple disciplines and have demonstrated the ability to solve research problems with experience in assay development, optimization, and troubleshooting • Adaptability and the ability to rapidly learn new technologies • Able to analyze and report data concisely and ability to multi-task and successfully interact with a diverse team of scientists to deliver results meeting the needs of various stakeholder groups
Preferred Experience: • Experience with LC-MS • Computational skills enabling automated data acquisition and analysis, and familiarity with related software applications (MS Access, Spotfire) • Experience in cell culture and cell-based assay • Familiarity in the use of automation and HTS instrumentation