Senior Assay Scientist at AstraZeneca in Waltham, Massachusetts

Job Description:

Senior Assay Scientist



Join AstraZeneca's Biologics Engineering (BE) team, where we turn ideas into life-changing medicines. We're looking for a Senior Assay Scientist to provide critical biochemical and cell assay expertise to support our expanding complex biologics and ADC portfolio. This is a lab-based role involving independent design, execution, and interpretation of scientific experiments, and effective communication of findings and recommendations as part of a multi-disciplinary project team.



Accountabilities:

As a Senior Assay Scientist, you will work in cross-functional teams to develop high throughput biochemical and functional assays and triage leads following antibody discovery campaigns. You will work collaboratively with our core facility to run flow and imaging-based assays to measure antibody binding, internalization, and potency. You will also work closely with automation experts and IT to establish high throughput assay platforms for screening different modalities.



Essential Skills/Experience:

- Master's Degree in Immunology, Biochemistry, Cell Biology or similar with at least 5 years of relevant experience in industry or academia OR
- PhD in Immunology, Biochemistry, Cell Biology or similar with 2 years' experience in industry or academia
- Experience with HT flow cytometry (iQue or Attune), SPR/BLI, and handling of primary cells and cell lines.
- Background in drug discovery in the pharmaceutical industry
- Experience and in-depth technical knowledge of assay development, screening and use of automation, with a dedication to quality and scientific rigor
- Strong teammate with good communication skills and experience of working in multi-disciplinary teams.
- Ability to tackle challenges creatively and contribute and improve assay technologies and processes



Desirable Skills/Experience:

- Ph. D. with industry experience.
- Experience in antibody design and characterization
- Project leadership experience
- Experience working in industry within matrix teams


At AstraZeneca, we are united by a shared passion to learn, grow, and discover. As Clinical Development Physicians and Scientists in Oncology, we push the boundaries of science to change the practice of medicine and transform the lives of patients living with cancer. We are a science-based, leading and decisive Oncology enterprise united in our vision to eliminate cancer as a cause of death. With one of the broadest and deepest Oncology pipelines in the industry, there are many opportunities to work with new and novel drugs and help discover what's next.



Are you ready to take our leading Oncology pipeline to the next level? Apply now!



AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.