Join a cutting-edge, clinical-stage precision immuno-oncology company focused on developing breakthrough treatments for solid tumors and hematological malignancies. This full-time, permanent role offers the opportunity to contribute to the advancement of a leading program developed by renowned scientists from Dana Farber, MGH, the Broad, and MIT. With over $120M raised from top-tier investors, the company is driving its clinical pipeline forward while expanding and validating novel therapeutic programs.
Open to all levels - title dependent on experience.
Job Summary
We are seeking a talented scientist with expertise in antibody discovery, engineering, and characterization. Reporting to the Senior Director of Antibodies, the successful candidate will play a pivotal role in discovering and optimizing therapeutic antibodies. This is a primarily lab-based position, with opportunities to collaborate on project teams, interact with CRO partners, and contribute to strategic decision-making.
Key Responsibilities
Design, construct, and screen antibody libraries to identify or optimize antibodies with desired properties.
Conduct biophysical characterization of antibodies.
Collaborate closely with the Biology group to accelerate program advancement.
Present and communicate research findings in group and project meetings.
Maintain thorough documentation of experimental work in electronic lab notebooks.
Qualifications & Education Requirements
BS with 5+ years, MS with 3+ years, or PhD in a relevant field (title will be based on experience).
Proven hands-on experience with yeast display and/or phage display.
Expertise in antibody affinity maturation, humanization, and related techniques.
Skilled in antibody biophysical characterization methods such as ELISA, binding kinetics (Octet/SPR), flow cytometry, DSF, and more.
Experience with alternative antibody formats like single-domain or bispecific antibodies is a plus.
Strong knowledge of therapeutic antibody development.
Ability to work independently, designing, executing, and troubleshooting experiments with minimal supervision.
A collaborative team player with excellent verbal and written communication skills, capable of thriving in a fast-paced environment.
Additional Information
Candidates must have the right to work in the U.S. and be available to start immediately.