We are seeking a highly motivated and creative scientist to join Immunology and Inflammation Therapeutic Area (I&I TA) located in Cambridge, MA. This position will work with the Type 2 Inflammation research team towards increasing our biological understanding of the role of IL-4 and IL-13 and the mechanism of action of Dupixent in dermal and respiratory diseases.
The successful candidate will be responsible for performing pre-clinical research that enhances our biological and therapeutic understanding of assets in clinical development and the life cycle management for multiple indications. The position requires an ability to work effectively both independently and in a collaborative team environment, as well as excellent technical/written/oral communication skills. The ideal candidate will be a driven bench scientist and excited to perform cutting edge research employing state-of-the-art technology.
A strong working knowledge and demonstrated track record in immunology and cellular and molecular biology is highly preferred. The ideal candidate should possess strong laboratory experience and technical expertise in in vitro cellular immunology (including ELISA, MSD, assay development, tissue culture, flow cytometry, primary immune cell assays, cell isolation) and ex vivo tissue processing and analysis.
Us02B
Responsibilities: • Work within the project team to design, execute, troubleshoot, analyze and document in vitro and in vivo experiments to drive research data package generation to support clinical and commercial development plans. • Serve as an integral project team member, who is expected to communicate data updates and recommendations within project teams and I&I Therapeutic Area. • Understand and adhere to corporate standards regarding code of laboratory conduct, safety, and appropriate handling of materials • Proficiency with electronic notebooks.
Qualifications: • BS in biology with 5+ years of research experience in laboratory setting/ MS/PhD in biology or Immunology with 3+ years of research experience in laboratory setting • Hands-on experience working with human and animal primary immune cells, such as PBMCs. • Experience with in vivo immunological experiments/techniques and ex vivo cultures. • Highly motivated, independent, collaborative and able to communicate effectively with a cross-functional team. • Possesses strong presentation skills and an exceptional work ethic. • Familiarity with technologies commonly used to assess immunological endpoints, including ELISA/MSD, western blot/JESS and multi-parameter flow cytometry. • Strong working knowledge and research experience in type 2 immunology (preferred).
Education: • BS • MS/PhD in biological science or Immunology (Strongly Preferred)
EEO:
"Mindlance is an Equal Opportunity Employer and does not discriminate in employment on the basis of - Minority/Gender/Disability/Religion/LGBTQI/Age/Veterans."