Early is Good (EIG) is developing non-invasive, multi-omic based tests to improve the accuracy and accessibility of cancer detection. Our Multi-omic Integration Platform combines DNA, RNA, protein, and metabolite detection into one test, providing earlier and more precise cancer diagnosis.
We're hiring a Nanoparticle Bioconjugation Scientist with extensive experience in nanoparticle science, bioconjugation, surface chemistry, and assay development. You'll be a key player in designing, developing, and scaling nanoparticle-based assays and surface modification strategies for high-sensitivity diagnostics. You'll also work closely with our cross-functional team to push the limits of cancer diagnostics.
Your responsibilities will include:
Design and develop nanoparticle conjugation methods for high-sensitivity assays
Optimize protocols for nanoparticle functionalization, including iron oxide and colloidal gold
Implement bioconjugation strategies like PEGylation, biotinylation, and covalent coupling with antibodies, antigens, nucleic acids, and small molecules
Troubleshoot and improve bioconjugation processes to enhance stability, sensitivity, and specificity
Collaborate with product development and scale-up teams to ensure consistent performance in nanoparticle assays
Maintain detailed experiment records, contribute to reports, and share insights with the team
Must have:
Ph.D/MsC. in Biochemistry, Chemistry, Materials Science, or a related field, focused on nanoparticle bioconjugation with 5+ years of industrial experience
Strong expertise in nanoparticle surface modification and functionalization
Hands-on experience with various conjugation chemistries, including thiol, amine, acid, azide, and other click chemistries
Proven success in developing particle-based immunoassays, like ELISA and lateral flow
Solid background in analytical methods for characterizing nanoparticles
Ability to work effectively as part of a cross-functional team
Nice to have:
Experience with scaling nanoparticle products for FDA-regulated markets.
Background in developing in vitro diagnostic assays, especially in oncology applications