Lead the department/team to participate in the comprehensive in vivo/early in vivo research and development project at all stages of drug development in preclinical stage, and help deliver high-quality drug candidates that can be used in preclinical research;
Cooperated and communicated with the new drug research and development project team and in vivo pharmacology-related CRO enterprises to carry out tolerance, pharmacodynamic evaluation and preliminary pharmacological studies of drug candidates using relevant in vivo animal models;
Designed in vivo efficacy experiment scheme, reviewed data, made statistical analysis, found problems and proposed solutions;
Qualifications:
PhD degree, major in pharmacology, animal medicine, immunology or biomedicine, with more than 10 years of research and development related work experience in the biomedical industry;
Proficient in the establishment methods of relevant animal models (including CDX, PDX, Syngeneic and humanized models), application scenarios and efficacy evaluation methods of anti-tumor/non-tumor drugs;
Familiar with the experimental techniques of pharmacokinetics, pharmacology and toxicology research, including in vivo experiments and the analysis and processing of experimental data;
Experience in coordinating and managing CRO organizations;
Strong innovative spirit and scientific and rigorous logical thinking ability, able to analyze and solve problems independently;
Good English reading and writing skills, able to independently consult literature, write relevant professional reports and declaration materials;
The specific job rank will be determined according to the comprehensive qualifications of the candidate.