Z-Alpha Therapeutics is a pharmaceutical company dedicated to the discovery and development of radiotherapeutics targeting key biological pathways for solid tumors. The company has a revolutionary technology platform in the next generation of alpha particle therapy with potential to be a more targeted therapy, increasing efficacy and limiting toxicity compared to competitors in the radiotherapeutics space. The company has a world-class team of scientists with decades of experience and foundational intellectual property that enables the potential to bring multiple drug candidates into the clinic.
JOB SUMMARY:
The Head of Biology will lead the discovery and validation of novel therapeutic targets in oncology, overseeing drug discovery activities from early-stage research to preclinical development. The position also includes mentoring project leaders, managing teams, and fostering cross-functional collaborations to accelerate oncology treatments toward clinical application.
ESSENTIAL DUTIES AND RESPONSIBILITIES:
Spearhead the discovery of new, high-value therapeutic targets for the oncology pipeline.
Develop and implement strategies for identifying novel targets within specific patient populations.
Oversee biology efforts for innovative oncology therapeutic programs, ensuring timely and strategic delivery of actionable data.
Prioritize projects and manage resources to support organizational goals.
Foster strong cross-functional collaboration within the discovery organization.
Effectively communicate scientific progress and strategy internally and externally.
Stay informed on competitive intelligence and advancements in oncology by interacting with experts, attending scientific meetings, and reviewing literature.
Promote a culture of scientific excellence and support career growth for a team of cancer biologists.
Support business development strategies and needs
Perform additional duties as assigned.
EDUCATION/KNOWLEDGE/SKILLS/ABILITIES REQUIRED:
Ph.D. in Biology-related field, with 12+ years of progressive biotech/pharma experience.
Deep understanding of oncology and the current therapeutic landscape.
Proven success in moving projects from target discovery to early development, including lead identification and optimization.
Strong interpersonal skills, capable of influencing key scientific decisions and collaborating with stakeholders. A strategic thinker able to balance the big picture with detailed program execution.
Strong leader who can develop and lead teams to a high level of performance, within an evolving and fast-paced environment.
Exceptional communication and presentation skills. Creative thinker who is innovative and open to new ideas and ways of working
Experience managing external research collaborations with contract research organizations and academic partners. Experience with regulatory filings (IND, IB, NDA) is preferred. Experience in radiopharmaceuticals is preferred, but not required.