The Process Development team is seeking a talented, highly motivated Scientist I to work on the purification of therapeutic antibody drug candidates from human and mouse immune repertoires. The successful candidate will provide downstream process development and material generation support within the company's Process Development team.
Primary Responsibilities for Role:
Develop, optimize, and scale-up purification processes for biologics candidates to support early stage development
Analyze and interpret data to drive technical understanding, meet project targets and objectives, problem solve, and make recommendations that drive efficiency, knowledge, and manage risk
Collaborate closely with other functional areas involved in antibody therapeutics development, including upstream process development, analytical development, project management, and cross-functional partners
Work effectively with external collaborators and CROs
Coordinate activities with functional groups and project teams
Discuss experiments and data with project team members
Develop, write, and review standard operating protocols and other technical documents
May act as a lead for assigned projects or team
Mentor and train other technical staff
Knowledge, Skills, and Abilities:
Experience in protein purification techniques, especially chromatography; antibody purification experience preferred
Proficient in writing methods and operating AKTA chromatographic instruments (such as AKTA Avant, AKTA Purifier, AKTA Pure, AKTA Ready or similar)
Strong scientific understanding and logical thinking
Ability to train others in basic laboratory techniques and equipment operation
Proficiency in analytical method development and analytical method validation
Demonstrate flexibility and problem-solving abilities