We seek a highly motivated and innovative scientist with immunology research experience and a passion to develop antibody-based therapeutics. You will play an integral role in the pre-clinical development of novel autoimmunity and inflammation therapeutics. The ideal candidate will have a proven track record of experience with core immunological assays and models (e.g., T cell proliferation, antigen recall, in vivo models of inflammatory disease) and techniques (immune cell culture, flow cytometry, ELISA, RT-PCR, etc.) The candidate will be required to coordinate and execute on research projects across multiple functional teams, both internal of IGMS and external vendors and collaborators. Strong communication skills and organizational skills are essential. A key initial responsibility will be the set up and establishment of core capabilities in the AI lab. This role involves delivering on programs through proof- of-concept in vitro and in vivo studies and advancing therapeutic candidates from early discovery to IND- enabling studies.
Responsibilities:
Establish core capabilities in AI lab
Lead research efforts to generate proof-of-concept in vitro and in vivo data for early-stage autoimmune and inflammation programs
Lead therapeutic candidate selection and perform IND-enabling studies
Work closely with team members and CROs to develop assays and models to assess biological activity
Present results at internal and external meetings
Qualifications:
Ph.D. with 2-7 years of industry experience or with equivalent postdoctoral research experience or a Bachelor's/ Master's degree with 10+ years of industry experience in the field of immunology.
Must have hands-on experience and proficiency in one or more of the following areas: multi-color flow cytometry, complex cell-based functional assays, in vivo mouse models of disease.
Must be proficient with Microsoft Word, Excel, and PowerPoint, GraphPad Prism, and FlowJo.
Experience establishing mechanistic in vitro and ex vivo immune cell-based assays with primary immune cells from human and relevant animal species.
Understanding of and ability to select relevant in vivo models for mechanistic and efficacy studies.
Demonstrated track record of independence, critical thinking, and scientific research achievements in immunology and/or significant contributions to a discovery program or therapeutic development.
Highly organized with reliable time-keeping skills and able to maintain a detailed and well organized electronic notebook.
Must have strong interpersonal, collaboration, and communication skills.
Being a team player and respectful of others is a must.
Able to thrive in a fast-paced, start-up environment.