AI ML Research Scientist at Mass General Brigham in Cambridge, Massachusetts

Job Description:

About Us:



As a not-for-profit organization, Mass General Brigham is committed to supporting patient care, research, teaching, and service to the community by leading innovation across our system. Founded by Brigham and Women's Hospital and Massachusetts General Hospital, Mass General Brigham supports a complete continuum of care including community and specialty hospitals, a managed care organization, a physician network, community health centers, home care and other health-related entities. Several of our hospitals are teaching affiliates of Harvard Medical School, and our system is a national leader in biomedical research.


We're focused on a people-first culture for our system's patients and our professional family. That's why we provide our employees with more ways to achieve their potential. Mass General Brigham is committed to aligning our employees' personal aspirations with projects that match their capabilities and creating a culture that empowers our managers to become trusted mentors. We support each member of our team to own their personal development-and we recognize success at every step.


Our employees use the Mass General Brigham values to govern decisions, actions and behaviors. These values guide how we get our work done: Patients, Affordability, Accountability & Service Commitment, Decisiveness, Innovation & Thoughtful Risk; and how we treat each other: Diversity & Inclusion, Integrity & Respect, Learning, Continuous Improvement & Personal Growth, Teamwork & Collaboration.



The Opportunity:



The Gene and Cell Therapy Institute (GCTI) is a newly created system-wide Institute under Mass General Brigham. The Institute will foster a world-class gene and cell therapy program that will leverage ongoing, groundbreaking scientific research efforts across the MGB system.


The mission of GCTI is to bring together the community of MGB investigators which can utilize gene and cell therapy platforms to achieve their scientific and clinical goals and improve the health of patients. The Institute will differentiate itself by harnessing the exceptional strengths of clinician scientists, the large and unique patient population, and major discoveries throughout the hospital system to propel MGB as the leader in Gene & Cell therapies.


The Abudayyeh-Gootenberg Gene Editing lab at the Mass General Brigham Gene and Cell Therapy Institute is seeking a talented AI Scientist and Engineer to join the Mass General Brigham Gene and Cell Therapy Institute. This role will work across multiple groups within the institute, including the Abudayyeh-Gootenberg lab, gene editing core, and RNA core. The successful candidate will contribute to developing AI solutions for gene and cell therapy, support general computational efforts, and help shape strategic directions for the institute.


This is a unique opportunity to work at the intersection of cutting-edge technology development and groundbreaking biomedical research. You will be part of a dynamic team focused on advancing gene therapy, cell therapy, stem cell biology, regenerative medicine, and biomanufacturing, through the application of advanced machine learning approaches. Your work will directly contribute to our understanding of large-scale data across different fields and the development of novel technologies and therapeutics.


As an AI Scientist and Engineer in our institute, you will play a crucial role in developing models to understand and model large amounts of biological data, including single-cell, genomics, and transcriptomic data. This work will ultimately yield predictive and generative models that can program biology and enable new technologies and therapeutics.


Your position will also be highly collaborative, involving close interaction with experimental scientists, computational biologists, and other researchers across the institute and labs. We actively encourage creativity and leadership from our computational experts, and you will have the opportunity to lead multiple projects within the institute. This role offers the exciting prospect of being at the forefront of AI applications in gene and cell therapy, with the potential to make significant contributions to the field.



Principal Duties and Responsibilities:



• Develop and implement AI and machine learning solutions for gene and cell therapy applications


• Independently perform research projects in collaboration with other teams in the institute


• Provide computational support to all projects and help with data analysis


• Participate in strategic planning for the institute's AI and computational initiatives


• You will develop pipelines for using cutting edge foundational models to represent large scale data, including single cell data, and make predictive interpretations.


• Developing software for machine learning based approaches for cell modeling and therapeutic development


• Organization and implementation of different data structures.


• Assists in the orientation and training of new computational staff.


• Write manuscripts for publication and manage code and data within the institute


• All other duties as assigned.



What We Offer:



• Opportunity to work at the forefront of AI applications in gene and cell therapy


• Collaboration with world-class researchers and cutting-edge technologies


• Access to state-of-the-art facilities and resources


• Potential to contribute to groundbreaking discoveries in regenerative medicine


• Supportive and innovative work environment that encourages creativity and leadership



Qualifications

Qualifications:



• Ph.D. in Computer Science, Computational Biology, Bioinformatics, or a related field


• Strong programming skills and experience with machine learning frameworks


• Expertise in processing and analyzing single cell data


• Familiarity with deep learning models and their applications in biological data


• Experience with large-scale data management and computing clusters


• Knowledge of molecular biology, stem cell biology, gene therapy, and/or cell therapy is highly desirable


• Excellent communication skills and ability to collaborate with multidisciplinary teams


• Strong organizational and project management abilities


• Ability to manage small teams towards high-level goals and priorities


• Demonstrated ability to work in a fast-paced, dynamic research environment



EEO Statement

Mass General Brigham is an Equal Opportunity Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.