Process Development Engineer - Oligo Chemist at Eurofins Genomics, LLC in Louisville, Kentucky

Job Description:

Eurofins MWG Operon LLC, a Eurofins Genomics company, is a member of the Eurofins Group with major offices and production facilities in the United States, Europe, and Asia, is an international provider of DNA sequencing services, DNA synthesis products, and bioinformatic services for academic and industrial research. The company's strengths are its strong customer orientation, fast service and high quality products including a series of advanced oligonucleotide design tools.

Eurofins is searching for a Process Development Engineer for Oligo Manufacturing in Louisville, KY. The Process Development Engineer will report directly to the Director of Operations.

Process Development Engineer responsibilities include, but are not limited to, the following:

• Develops, validates, and implements new processes for Oligonucleotide Synthesis, Deprotection, Purification, and Quality Control in a high throughput production environment
• Analyzes and improves current production processes
• Designs and implements methods and protocols for robotic equipment such as liquid handlers and oligonucleotide synthesis robots
• Validates and adapts new robotic equipment to support the automation of the production processes
• Collects, documents, and analyzes experimental data
• Translates manual research protocols into automated production processes
• Writes SOPs for new production processes, trains production associates for new processes and supervises the process implementation
• Interacts with all members of the R&D team
• Communicates effectively with all levels of production and management
• Coodinates with production and maintenance for the evaluation and implementation of new equipment and processes
• Ensures that all processes conform to ISO 9001-2008 and ISO 13485 standards

The Ideal Candidate Would Possess

• Thorough understanding of oligonucleotide chemistry, including phosphoramdite based synthesis methods, deprotection and purification methods, and post-synthetic labeling chemistry
• Experience in oligonucleotide quality control, including MALDI-Tof and ESI mass spectrometry, HPLC analysis and capillary gel electrophoresis
• Proficiency operating oligonucleotide purification equipment, such as Dionex, Aekta, and Gilson HPLCs
• Proficiency using high throughput robotic equipment for liquid handling, such as Hamilton, Tecan, and Agilent robots
• Proficiency operating automated oligonucleotide synthesis equipment, such as ABI 3900 and Dr. Oligo
• Experience with ISO 13485 and cGMP
• Strong troubleshooting capabilities
• Experience in documenting and analyzing experimental data
• Strong computer, scientific, and organization skills
• Excellent communication (oral and written), and attention to detail
• Proven ability to work independently and as part of a team
• Self-motivation, adaptability, and a positive attitude
• Ability to learn new techniques, perform multiple tasks simultaneously, keep accurate records, follow instructions, and comply with company policies

Basic Minimum Qualifications

• College degree, or equivalent, in Biochemistry, Chemistry, Biology, or related area of science
• 3 years of experience in high throughput oligonucleotide manufacturing and process development

This position is full time, Monday to Friday, 8am - 5pm, with overtime as needed. Candidates currently living within a commutable distance of Louisville, Kentucky are encouraged to apply.

As a Eurofins employee, you will become part of a company that has received national recognition as a great place to work. We offer excellent full-time benefits, including comprehensive medical coverage, life and disability insurance, 401(k) with company match, paid holidays and vacation, personal days, and dental and vision options.

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