Adherence to all Good Manufacturing Practices (GMP) Safety Standards, Office
Job Description
Thermo Fisher Scientific Inc. is the world leader in serving science, with annual revenue exceeding $25 billion. Our Mission is to enable our customers to make the world healthier, cleaner and safer. Whether our customers are accelerating life sciences research, solving complex analytical challenges, improving patient diagnostics and therapies or improving productivity in their laboratories, we are here to support them.
Make an impact!
This is a key position within the Transplant Diagnostics R&D Bioinformatics team, based in West Hills, CA. The successful candidate will have the opportunity to partner with lab scientists, data analysts, software engineers and domain experts to build pioneering technologies and develop innovative molecular typing and antibody detection products.
The successful candidate will develop, improve, and maintain tools, pipelines, and software for the analysis of complex HLA typing data from PCR, microarray, NGS, and antibody detection platforms. This role will work in collaboration with the research staff and other departments, and requires knowledge of data analysis methods, software development, bioinformatics, statistics, molecular biology, as well as the ability to quickly grasp new subject areas.
What will you do?
Build software tools, including development and implementation of new computational algorithms, machine learning and statistical models to provide solutions for process automation and data analytics for the R&D and manufacturing teams
Develop pipelines for NGS analysis and other bioinformatics workflows
Build and maintain an internal Bioinformatics web portal for communication and distribution of Bioinformatics tools throughout the Transplant Diagnostics division
Search relevant sequence information from external sources for primer and probe design, as well as mining and analysis of genomic libraries and genomes
Analyze and interpret complex experimental results and work hand in hand with laboratory scientists for the research and development of new molecular and antibody products
Collect, clean and manage data from various sources, including Excel spreadsheets, text files and SQL databases
Actively participate in software development lifecycle, including writing software specifications, code and design reviews, implementing test plans
Regularly communicate accomplishments and progress to team members and management
Education / Experience
PhD from an accredited higher learning institution with studies in Computer Science, Bioinformatics, Computation Biology, Life Sciences/Molecular Biology or related field AND 2 years of related postdoctoral or industrial experience; OR master's degree in Computer Science, Bioinformatics, Computational Biology, Life Sciences/Molecular Biology or related field AND 4 years of related work experience; OR bachelor's degree in Computer Science, Bioinformatics, Computational Biology, Life Sciences/Molecular Biology or related field AND 6 years of related work experience
Experience developing analytical software tools using programming languages, such as C#, Python, R, JavaScript, and SQL
Experience developing relational databases
Experience in developing web tools and services
Experience with cloud technologies such as AWS and docker
Knowledge, Skills, Abilities
Proficiency in building and maintaining NGS or other bioinformatics analysis pipelines
Proficiency working in Windows and Linux environments
Pragmatic self-starter who is proactive, self-motivated, team-oriented, and customer-focused with a strong work ethic
Ability to meet deadlines within a dynamic environment and able to handle multiple tasks simultaneously while adapting to changing priorities
Be curious, detail oriented, and analytical, with a proven ability to learn quickly
Sound understanding of statistics, machine learning algorithms, the ability to generate robust predictive models for multidimensional data
Proactively learns products and new projects and stays ahead with Bioinformatics, computational or industry trends
Good verbal and written communication and well-founded problem-solving skills
Demonstrated skills in project management and formal continuous process improvement techniques
Ability to work effectively in collaboration with diverse groups of people
Preferred Qualifications
Knowledge of immunology, HLA
Experience administrating a Linux system
Understanding wet lab techniques and principles in the field of Molecular Biology, Genomics, and/or Biochemistry
Compensation and Benefits
The salary range estimated for this position based in California is $95,900.00-$143,825.00.
This position may also be eligible to receive a variable annual bonus based on company, team, and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on, which includes:
A choice of national medical and dental plans, and a national vision plan, including health incentive programs
Employee assistance and family support programs, including commuter benefits and tuition reimbursement
At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy
Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan
Employees' Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount
For more information on our benefits, please visit: https://jobs.thermofisher.com/global/en/total-rewards