Pace® makes the world a safer, healthier place. We advance the science of our pharmaceutical and biopharmaceutical customers through the drug development process, from early-phase R&D through clinical trials and GMP commercial product support. For customers with in-house manufacturing and labs, Pace® provides professional services to support their operations.
Job Description Oligonucleotide Chemist Pace® Life Sciences is a premier Contract Research and Development Organization located just north of Cambridge, MA providing pharmaceutical development services for small molecules, protein biologics, oligonucleotide and mRNA therapeutics, and other innovative drug candidates.
Summary We seek a highly motivated chemist with experience in the design and synthesis of oligonucleotides to support drug discovery and development programs. Our clients include biotechnology and pharmaceutical companies from new startups to those with global operations. Competitive applicants will be able to demonstrate an in-depth knowledge of the solid phase synthesis of therapeutic oligonucleotides and their analytical characterization, conjugation chemistries to attach oligonucleotides to proteins, an ability to collaborate in a dynamic and fast changing environment, creative problem solving, and excellent oral as well as written communication skills. This is a full-time scientist position in Woburn, MA with title commensurate to experience.
Responsibilities include: • Independently design and execute experiments, analyze data, and understand the reliability of results. • Present results and planned experiments clearly and concisely both verbally and in written reports. • Maintain a strong awareness of scientific literature relevant to expertise and assigned projects. • Maintain equipment and troubleshoot problems as needed. • Continuously improve technical skills and acquire knowledge specific to the pharmaceutical industry.
Required background and experience includes: • Ph.D. in chemistry, chemical engineering, biochemistry, or closely related discipline with 0 - 3 years' of industry experience or M.S./B.S. with 5+ year's industry experience synthesizing oligonucleotides and/or peptides is required. • Hands-on experience with oligonucleotide or peptide sequencers as well as common analytical instruments and techniques (e.g., UV/Vis, HPLC, LC-MS) for analysis of synthetic products. • Experience with highly modified therapeutic oligonucleotides (e.g., ASO, siRNA, sgRNA) and ability to conjugate oligonucleotides to peptides/proteins or lipids is highly desired. • Established track record of significant contributions as an individual technical expert as well as the ability to thrive in a multi-disciplinary team environment. • Outstanding written and oral communication skills as well as polished presentation skills. • Flexibility and outstanding time management skills.
PHYSICAL/MENTAL REQUIREMENTS: The physical demands described herein are representative of those that must be met by an employee to successfully perform the essential functions of the job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
Mobility to work in a lab and office setting, use standard office and lab equipment and stamina to sit for extended periods of time; exerting up to 20 pounds of force occasionally and/or up to 10 pounds of force frequently to lift, carry, push, pull or move objects; vision to read printed materials and computer screens; and hearing and speech to communicate in person or over the telephone. Senior Scientists will be required to work longer days from time to time to complete a project or finish job responsibilities.
WORKING ENVIRONMENT: Work is performed in a lab and office setting. Work is subject to chemicals, fumes, gasses, noxious odors and related items in a lab setting.
OFCCP Statement: Pace® Life Sciences, LLC is an Equal Opportunity Employer and will not discriminate against any applicant for employment on the basis of race, age, religion, sex, veterans, individuals with disabilities, sexual orientation, or gender identity.
Additional Information
Benefits
80 hrs of paid vacation per year, 7 paid holidays per year, 2 floating holidays per year (prorated based on start date), 40 hrs paid sick time per year, paid bereavement leave (days based on relation to the employee), 8 hrs paid volunteer time per year, medical, dental, vision, voluntary short-term disability, long-term disability, life insurance, voluntary supplemental life insurance, traditional 401k and ROTH 401k with a company match, HSA, FSA, employee referral bonus, employee assistance program, tuition reimbursement program, employee recognition program, voluntary ID theft coverage, voluntary legal coverage, voluntary accident insurance, voluntary hospital indemnity insurance, and voluntary critical illness insurance.
Equal Opportunity Employer
Pace® provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, creed, color, religion, genetics, protected veteran status, national origin, sex, age, disability, marital status, sexual orientation, gender identity or expression, citizenship, or any other characteristic protected by federal, state or local laws. This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation and training.
Work Schedule Monday through Friday, 8:00 AM - 5:00 PM