Associate Scientist II/Sr. Associate Scientist at Bionova Scientific LLC in Fremont, California

Job Description:

The Asahi Kasei Group operates with a commitment of creating for tomorrow. Our business sectors, Material, Homes, and Health Care, contribute to the development of society by anticipating the changing needs of those around the world. We look for candidates that offer a fresh perspective and a variety of skills to help us achieve our commitment.



Bionova is a rapidly growing, biologics CDMO focused on developing and manufacturing recombinant protein products using mammalian cell culture processes. Our business success is built on bringing together top scientific talent, arming them with the best available tools, and setting them loose in an agile, energized culture focused on solving difficult client problems. Because our success depends on our ability to exceed our clients' expectations, we look for candidates with an innate desire to serve. Adaptability and an interest in transformative action are also common attributes among our team. Bionova became a subsidiary of Asahi Kasei Medical in May 2022, a division of Tokyo-based Asahi Kasei Group. This acquisition has enabled Bionova to greatly accelerate growth of the business, both in capacity of current service offerings and expansion into new service offerings.



Company:

Bionova Scientific LLC



Job Description:




Position Summary:



The Associate Scientist II, Formulation Development will design, prepare and characterize the different formulations for the drug product. Will conduct pre-formulation and formulation characterization studies to support drug product development. This involves performing lab activities, analyzing the data, planning studies, communicating and presenting lab results to cross-functional team members and clients as required.



Essential Duties and Responsibilities:

• Designs & develops formulations for monoclonal antibodies, antibody drug conjugates, bispecifics and fusion proteins from development programs for preclinical and clinical studies (liquid and lyophilized forms).


• Prepares and runs samples for the characterization of the stability samples. Will require various techniques (TFF, IEX, SEC, Fluid Imaging, CE-SDS, pH, etc.).


• Monitors stability and incompatibility of formulations.


• Summarizes and presents characterization data on formulations in reports and presentations prepared and issued in a timely manner.


• Conducts troubleshooting of pre-formulation & formulation challenges and recommends potential solutions.


• Collaborates with members of the Formulation Development and/or Analytical Development groups on projects in discovery & clinical development.


• Evaluate new technologies and innovations to improve operational efficiency or expand department capabilities.


• Maintains appropriate experimental records in electronic laboratory notebooks.

Working Conditions:

• This position requires working in a lab/office setting. The role requires walking, standing, stooping, kneeling, and crouching. The employee must occasionally lift and or move up to 20 pounds independently.

Qualifications:

• BS or MS in Biological Sciences or related disciplines with 2+ years of relevant research and/or industry experience in Analytical development and Formulation development.


• In-depth understanding of protein chemistry and industry-standard analytical tools (CE, HPLC/UPLC, Mass Spec, ELISA, Fluid Imaging, compendial assays, etc.)


• Hands-on experience with planning and analyzing data through Design of Experiment (DOE).


• Ability to troubleshoot assay failure related to equipment or execution and identify root cause.


• Creative thinker that can identify better and more efficient methods to address issues and gaps.


• Demonstrate ability to work independently and on cross-functional teams.


• Strong attention to detail.


• Effective verbal and written communication skills.


• Enthusiastic learner.

Compensation Range: The base compensation range for this role is between $75,000 and $85,000. However, the actual compensation may vary depending on your experience and qualifications.


Health Benefits and Program: Bionova offers health benefits at a subsidized rate.


Healthcare, Dental, and Vision insurance


Life Insurance and Disability Program: 100% covered by Bionova.


Retirement Plan (401K) Up to 8% of Employer Match


Paid time off up to two weeks


10 days of Holidays and 5 days of Sick Leave.


As an equal opportunity employer, Asahi Kasei believes a diverse workforce will provide us with the ability to continuously support the changes in the economy, society, and environment. Apply Now