DropXcell is revolutionizing drug discovery by quantitatively screening millions of drugs for function while shortening the screening time by months. By screening 10,000-times more drugs, more and better drug nominations will be taken to the clinic. By screening more quickly, we can cut drug development times significantly and tackle more disease programs for less cost. Together, our technology will derisk drug development and bring better therapies to patients.
DropXcell is hiring an experienced Co-Founder to help strategically guide the company as it prepares to enter into drug development partnerships and significant growth. Together with the CEO, you will lay the groundwork for the company's success and help to develop our platform technology for prime-time.
Responsibilities
Manage CRO relationships and workflows for cell engineering, sequencing, animal studies, and other research and preclinical work
Execute discovery partnerships to find and characterize top drug candidates using our high-throughput functional screening platform
Lead future pipeline development efforts, including disease and target identification and development of hits discovered with our platform technology
Lead the development and optimization of novel methods for antibody library creation, cell engineering, functional screening, and antibody sequencing, as well as implementing standard workflows as appropriate
Help hire and mentor team as company expands
Help to develop a positive company culture that is people-focused and science-forward
Must-haves
Prior experience successfully building a biotechnology startup in a leadership role (C-suite, VP, or Director level), preference given to successful exit, IPO, or self-sufficiency
Prior leadership of drug discovery and development, such as in early-stage discovery or evaluation of lead candidates prior to IND. Preference having experience taking compound(s) from discovery, to lead, to IND
Deep scientific expertise in molecular biology, cell-line development, in vitro and in vivo assay development, and/or sequencing
Organized and driven leader with ability to strategically prioritize and execute in a fast-paced startup environment
Resourceful and willing to wear multiple hats
Desire and ability to regularly commute to our lab in Newton, MA outside of Boston
Desire to revolutionize drug discovery!
Nice-to-haves
In-depth knowledge of antibody therapeutic and cell therapy modalities in cancer and/or auto-immune disease
Knowledge of variety of antibody formats, such as bispecifics and multispecifics, as well as key development challenges for different formats
Prior experience in big pharma
Strong and demonstrated network of contacts for potential discovery partnerships and future investment
Knowledge of typical deal structures for pharmaceutical asset partnerships and licensing
Experience in program development and target identification
Experience in performing high-throughput screens in pre-clinical discovery
Familiarity with methods and use of AI in drug discovery