12-month contract to start with the possibility of extension or conversion depending on performance.
Rate: $40-43 (Master's level I) or $44.00-$52.84 (PhD level II)
Location: Lexington, MA
Job Description:
The Research Scientist RNAi formulations and Biophysics will be based in GNAT Research. The Research Scientist s a lab based role with hands on formulation, biophysical and analytical characterization expertise of oligonucleotides for injectable delivery.
Reports to Team manager/Senior Director of Nucleic acid Delivery, Formulations and Bioanalysis.
Interacts with peers who specialize in non-viral delivery manufacturing and characterization, Oligonuclotide chemistry and stability assays, PK and Bioanalysis of Oligonucleotides
As a Sci I in the Nucleic Acid Delivery, Formulations & Bioanalysis overall department, you will become a part of a multinational and diverse team consisting of Reseach Associates, Specialist/Scientists. The goal of the team is to develop preclinical formulations of conjugated oligonucleotides apply advanced analytical characterization techniques and translate these to preclinical and clinical studies through internal and external collaborations in an automated high throughput manner.
Identifies gaps in technological capabilities provides recommendations to guide the research agenda
Manage multiple external collaborations for deliverables
Optimize long-term storage and stability conditions of RNAi conjugates and oligonucleotide formulations in general
Develop robust analytical methods and assays for QC and developability assessments
Communicate findings internally to team via presentations and written reports
Ability to thrive in a multi-disciplinary and fast-paced research environment with tight deadlines
Required Skills:
3 years of relevant experience with a PHD (LEVEL II) or 3+ years of relevant experience with a Masters (LEVEL I)
Lab experience in formulation of siRNA or oligonucleotides for systemic delivery
Hands on Analytical characterization of oligonucleotides
Experience in project management and collaborating with external CMO's.