We are seeking an experienced Clinical Trial Enrollment Manager with advanced expertise in Central Nervous System (CNS) disorders to lead patient recruitment and enrollment strategies across our expanding portfolio of clinical trials. The ideal candidate will have demonstrated success in accelerating enrollment timelines while maintaining quality and compliance standards. This position will initially focus on our ongoing adolescent ADHD studies, with upcoming trials in depression and Alzheimer's disease.
Key Responsibilities:
Strategic Enrollment Planning & Execution
Develop comprehensive, data-driven enrollment strategies for CNS clinical trials
Establish realistic site-level enrollment projections based on historical performance and current landscape analysis
Implement innovative recruitment approaches tailored to specific patient populations
Lead root cause analysis for enrollment challenges and develop targeted intervention plans
Collaborate with cross-functional teams to align enrollment strategies with overall program timelines
Site Management & Optimization
Conduct regular site performance reviews using defined metrics and KPIs
Lead productive, solution-oriented meetings with sites to address enrollment barriers
Create and implement site-specific enrollment acceleration plans for underperforming sites
Provide specialized training and resources to optimize site recruitment capabilities
Make data-driven recommendations for site additions or closures based on enrollment performance
Cross Functional Leadership
Partner with medical, regulatory, and operational teams to implement protocol amendments that could improve enrollment feasibility
Collaborate with data management teams to track and analyze enrollment metrics
Work with finance to optimize resource allocation for recruitment initiatives
Liaise with CROs and vendors to ensure alignment on enrollment strategies and performance expectations
Present enrollment status and forecasts to senior leadership and stakeholders
Qualifications & Experience
Advanced degree required (PhD, PharmD or MD) in life sciences, healthcare, or related field
Additional certifications in clinical research or project management (PMP, CCRA) highly desirable
Minimum 7-10 years of clinical research experience with at least 5 years focused on enrollment management
Demonstrated expertise in CNS trials, particularly in ADHD, depression, and/or Alzheimer's disease
Proven success in accelerating enrollment in complex, competitive clinical trial environments
Track record of developing and implementing innovative recruitment strategies
Experience with global trials preferred
In-depth understanding of CNS disorder patient pathways and treatment landscapes
Familiarity with diagnostic criteria and assessment tools for ADHD, depression, and cognitive disorders
Knowledge of age-specific recruitment challenges and solutions (adolescent, geriatric populations)
Understanding of regulatory considerations for recruitment in vulnerable populations
Expertise in analyzing enrollment metrics and forecasting models
Strategic problem-solving and analytical thinking
Strong leadership and influencing abilities
Excellent communication and negotiation skills
Data interpretation and visualization capabilities
Meeting facilitation and stakeholder management
Ability to drive change and implement new approaches
Experience implementing innovative digital recruitment strategies
Background in behavioral health or psychiatric research
History of successful protocol amendments to improve enrollment feasibility
Experience with community engagement and patient advocacy group collaboration
Advanced proficiency in enrollment analytics and predictive modeling
This position offers the opportunity to make significant contributions to the advancement of treatments for important CNS conditions, working with a collaborative, mission-driven team focused on bringing innovative therapies to patients.