Research Scientist at Partner's Healthcare in Cambridge, Massachusetts

Job Description:

Site: Mass General Brigham Incorporated


At Mass General Brigham, we know it takes a surprising range of talented professionals to advance our mission-from doctors, nurses, business people and tech experts, to dedicated researchers and systems analysts. As a not-for-profit organization, Mass General Brigham is committed to supporting patient care, research, teaching, and service to the community. We place great value on being a diverse, equitable and inclusive organization as we aim to reflect the diversity of the patients we serve.


At Mass General Brigham, we believe a diverse set of backgrounds and lived experiences makes us stronger by challenging our assumptions with new perspectives that can drive revolutionary discoveries in medical innovations in research and patient care. Therefore, we invite and welcome applicants from traditionally underrepresented groups in healthcare - people of color, people with disabilities, LGBTQ community, and/or gender expansive, first and second-generation immigrants, veterans, and people from different socioeconomic backgrounds - to apply.



Job Summary
The Gene and Cell Therapy Institute (GCTI) is a newly created system-wide Institute at Mass General Brigham (MGB) built to support the translation of MGB's world-class research into gene and cell therapies. The Institute differentiates itself by providing a foundation of gene and cell therapy expertise, manufacturing capabilities, and regulatory support to harness the exceptional clinician scientists, research groups, and large and unique patient population that comprise the MGB hospital system to advance medicine.


We are seeking a motivated and skilled Core Manager to join our RNA Therapeutics Core team and participate in the development of novel RNA-based medicines and technologies. The candidate who fills this role will oversee a small team of skilled scientists and technicians and manage day-to-day Core and laboratory operations. Specific duties include managing a small team of lab personnel, promoting a positive work environment through occasional team building activities, interfacing with academic and industry Core customers, fulfilling orders, ensuring accurate and complete record-keeping and sample tracking, and overseeing raw material supply and access.


The successful candidate will have laboratory management experience, personnel management experience, and significant expertise in molecular biology. They would be detail-oriented and organized, a proficient multitasker, an active contributor to a positive work environment, and eager to work as part of a team. Optionally, the ideal candidate would have expertise managing a GMP manufacturing facility or operating in a GMP environment.



Qualifications



PRINCIPAL DUTIES AND RESPONSIBILITIES:

• Manage one or more direct reports, assign tasks, and ensure high quality and timely execution of work

• Oversee d evelop ment of new processes for RNA synthesis and purification with guidance from PI , and guide implement ation of these processes on automation platforms

• Facilitate the setup of a sample intake and tracking system, and manage the system to initiate and fulfill synthesis projects for external parties ; communicate with external parties as needed

• Manage the Core budget and business plan; track costs and revenues

• Manage consumables supply and stocks , equipment maintenance contracts

• Assist with wet lab work as needed until technical resources are in place

• Oversee generation of high quality circular RNA and mRNA

• Enforce standard lab safety precautions and proper personal protective equipment usage; complete requisite trainings as appropriate

• Participate in lab meetings and generate ideas for improving efficiency and productivity in the lab's operations

• Communicate effectively with the team, discuss progress, and share operational data with supervisors

Additional Job Details (if applicable)


Hybrid role M-F Eastern Business Hours required, onsite in office required and remote days require stable, secure, quiet, compliant work station.



Remote Type


Hybrid



Work Location


65 Landsdowne Street



Scheduled Weekly Hours


40



Employee Type


Regular



Work Shift


Day (United States of America)



EEO Statement:


Mass General Brigham Incorporated is an Equal Opportunity Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.




Mass General Brigham Competency Framework



At Mass General Brigham, our competency framework defines what effective leadership "looks like" by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline. Apply Now