Please reply with a CV to careers@allinbio.com if interested.
ALLInBio, Inc. is developing a precision immunology approach that allows the selection and early treatment of "at-risk" patient populations that are genetically predisposed to rapidly progress and develop severe disease. Through this approach, we will shift patient care in chronic inflammation from treating symptoms to addressing the root cause of disease.
About the Role
ALLIn Bio, Inc. is seeking an experienced and self-motivated medicinal chemistry leader who is capable of leading and executing discovery projects from hit identification to development candidate selection and beyond. The candidate should be a motivated drug hunter with a strong record of accomplishment in medicinal chemistry specifically and small molecule drug discovery in general and is competent in managing external CROs to deliver the results. This role will report directly to Vice President, Medicinal Chemistry and Technical Operations.
What You'll Do
Apply the key principles of medicinal chemistry, literature precedent, and drug design to direct medicinal chemistry programs in discovery stage, including hit identification, lead optimization, and development candidate selection
Lead or co-lead a discovery stage small molecule program, set the program strategy, design compounds, manage CROs, and drive SAR development forward
Manage ADME/PK, scale ups that are associated with the program whenever necessary
Present the rationale, strategy, and updates of the program chemistry efforts to scientists in other disciplines and to senior management
Understand and apply computational tools to the design of molecules
Think strategically in prioritizing series and allocating resources
Contribute to the operation of the functional group
Contribute to patent and scientific publication writing
What You'll Bring
PhD in organic chemistry with 15+ years of direct experience in biotech and or pharma
Demonstrated capability in medicinal chemistry and small molecule drug discovery
A strong command of ADME/PK, preclinical safety, and basic pharmacology
Familiar with tools in SBDD
Experienced in multidisciplinary, dynamic and matrixed team environment
Effective in collaboration with teammates with diverse background
Strong organizational skills
Self-motivated, driven, strong problem-solving skills and scientific creativity
Strong track record supported by a significant publication record, filed patents and presentations.
Excellent written and oral communication skills
Prior experience in autoimmune and CNS disease areas is a plus
Please reply with a CV to careers@allinbio.com if interested.