Education Minimum Requirement: • Bachelor's degree in Engineering, Automated Sciences, Computer Science, Biology, Chemistry or equivalent with scientific expertise with laboratory equipment in the development and execution of bioanalytical assays
Required Experience and Skills: • Experience with liquid handling systems - (e.g. Hamilton, Labcyte, Beckman, Tecan, Brooks) • Experience working with or programming automated laboratory devices such as washers, dispensers, centrifuges. • Excellent verbal and written communication • Ability to generate, evaluate, and understand scientific data generated on robotic platforms • Must be self-sufficient and be able to hit the ground running
Preferred Experience and Skills: • Integrating robotic system schedulers (e.g. High Resolution BioSolution, Biosero, Thermo) • Working in pharmaceutical or biotech company and/or laboratory experience • Implementing novel automation workflows and authoring operations SOPs • Microsoft programming languages (VB, C#, labview or equivalent) • Electro-Mechanical design/assembly skills • Use of electronic laboratory notebooks
Responsibilities:
The automation scientist in DMPK at South San Francisco will be responsible for driving the implementation of automated workflows to support pre-clinical studies. The Scientist will work collaboratively with other team members in a fast-paced environment to operate automated laboratory equipment and systems to support various DMPK assays. This specific position is a 1-year contract, and the individual should possess knowledge of the principles and concepts of various biological assays as they pertain to method development and sample testing using various liquid handlers and laboratory equipment. They should have a propensity towards technology. The successful candidate will play a crucial role in laboratory automation and modernization, providing input into the optimization of experimental methods with laboratory equipment and automation using state-of-the-art robotic systems. • Oversee and drive the design, planning, and execution of robust automation strategies to support the DMPK group in SSF • Work jointly with department members, IT, and across functional teams to implement automation workflows, support lab instrumentation and robotic platforms, and develop novel data handling and analysis workflows • Contribute to the development of automated workflows to support assays such as immunoassay (IA), peptide stability, protein binding, automated sample preparation for plasma and tissue drug concentration analysis, cell culture maintenance & cell-based assays • Map and integrate all the workflows for efficient use of automation and space • Develop/update operations SOPs • Troubleshoot errors, maintain, and update instruments • Train scientists in automation workflows & platforms Manage data integrity through automated processes • Collaborate to identify, evaluate, and recommend novel and cutting-edge automation and assay strategies to drive our discovery programs, including machine learning and artificial intelligence"
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