Research Fellow at Mass General Physicians Organization(MGPO) in Boston, Massachusetts

Job Description:

The Center for Precision Imaging (Director: Umar Mahmood, MD, PhD) at the Massachusetts General
Hospital Martinos Center/Harvard Medical School has openings for highly qualified individuals at the
post-doctoral level with strong background in preclinical PET molecular imaging and interest in
molecular imaging of cancer. Our Center is at the forefront of personalized PET molecular imaging and
we are working to pioneer novel precision imaging and therapy approaches. We have a long-standing
interest in developing and translating targeted biological PET probes for improved tumor characterization
for personalizing cancer treatment and autoimmune conditions. Over the past decade, we have
produced many PET and optical imaging probes for assessing immune system activation, receptor
imaging, imaging of the tumor microenvironment and interrogation of metabolome. Our group has led
some of the first efforts to diagnose therapeutic resistance through receptor imaging and feedback loop
signaling, monitor and predict the immune response in cancer immunotherapy and utilize targeted
imaging to determine effective therapy dosing, among others. These efforts have led to two first-inhuman
imaging agents, most recently 68Ga-NOTA-hGZP for imaging granzyme B, currently in open trials
for clinical validation.
Selected candidate(s) will be involved in a wide range of preclinical imaging projects using our
proprietary PET probes for imaging and therapeutic radiopharmaceuticals for treatment of cancer.
Candidates should have a PhD degree and ideally previous experience in PET image acquisition, image
analysis, radiolabeling with radiometals, working with small animal models and basic wet lab skills.
Proficiency in scientific writing is strongly desired. Interested candidates should email a cover letter, CV
(including a full list of publications), a statement of research interests and goals and the contact
information for 3 referees. Please send to umahmood@mgh.harvard.edu.



Qualifications

Requirements
PhD in chemistry, biochemistry, biomedical engineering, molecular biology or related fields
Interest in cancer molecular imaging and radiotheranostics
Previous experience with preclinical PET imaging and/or radio-labeling with radiometals
Experience with PET image analysis
Previous experience with routine laboratory techniques such as cell culturing, Western blot, IHC, and
flowcytometry is preferred.
A track record of productive research and publications
Excellent verbal and written communication skills



EEO Statement

Massachusetts General Hospital is an Equal Opportunity Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. Applications from protected veterans and individuals with disabilities are strongly encouraged.