We are seeking a highly skilled and motivated scientist at the Scientist II level to join our Immunology and Respiratory Disease Department located in Ridgefield, CT. The successful candidate, with a demonstrated ability to work in a matrix environment, will work within the Translational Biology group to develop in vitro cellular models relevant to fibrotic diseases. Candidate will work in a highly collaborative group and will support research projects that aim deliver innovative drug concepts for clinical development
Responsibilities:
Work with lab managers and team members to plan and execute cellular assays using primary human cells. Experience with 2D and 3D cultures is a plus.
Execute relevant cellular/molecule functional assays (ELISA, TaqMan qPCR, color-metric based assays etc.) and cell-based imaging with minimal supervision.
Perform literature searches and extract relevant information from published protocols and implements them; demonstrate the ability to interpret outcome of experiments and to propose appropriate follow-up.
Effectively communicate work orally and in writing; independently complete high quality work notebook and contribute to writing protocols and provide input for scientific reports; demonstrate agility in learning new techniques and adaptability to a matrixed work culture.
Work in a collaborative manner with other members in the department; participate in cross departmental project teams when needed.
Report and treat data with a high level of integrity and ethics; comply with applicable regulations, perform all work in a safe manner; maintain proper records in accordance with SOPs and policies.
Skills:
Previous hands-on experience in tissue culture is a must (primary human cell culture experience is a plus).
Practical experience in basic molecular assays such as RNA isolation, qPCR, and/or ELISA is preferred.
Practical experience or knowledge in imaging based cellular assay (i.e., immunofluorescence, live-cell imaging) is a plus.
Proficient with basic analysis software such as Excel (must) and GraphPad Prism (preferred).
Strong ability to work in a matrix environment
Education:
Bachelor's Degree with 3+ years' experience or Master's Degree in immunology, molecular biology, biochemistry, or equivalent experience in related field