Job Description: • The QTAS Department is seeking a highly motivated scientist to support the development and implementation of single cell-based flow cytometric (FCM) assays that enable development of novel therapies from the bench to the clinic. • The desired candidate will work in a highly collaborative environment to develop pharmacodynamic assays that support internal decision making for preclinical studies and Ph1 clinical trials. • In this laboratory role, the ideal candidate will perform hands-on assay development and will execute established assays to support candidate therapeutic modalities. • The work encompasses immunophenotyping in varying matrices and optimizing FCM assays for fit-for-purpose use. • The ideal candidate will have a strong background in biology, immune-oncology, immunology, molecular biology, biochemistry, or cancer biology and will be supervised by an established subject matter expert.
Responsibilities • Work as part of a highly collaborative interdisciplinary team in an integrated early drug development laboratory. • Work with different bioanalytical matrices to support FCM assay development. • Conduct laboratory experiments to characterize and optimize flow cytometric assays. • Execute existing pharmacodynamic assays using established SOPs to support early stage immune-oncology and immunology R&D projects in a detail-oriented approach.
Experience • 3 - 5 years relevant experience Experience with mammalian cell culture and/or isolating primary cells. Strong communication skills - verbal, written, and scientific data presentation. Ability to multitask and highly attentive to detail. • Ability to learn, understand, and execute new scientific techniques. Proficiency with Microsoft Office software, including excel and word; ability to learn new software applications.
Preferred Skills • Strongly preference towards candidate with 2+ years of flow cytometry experience; experience with various BD instruments (i.e. Fortessa, Symphony) is highly desirable. • Experienced with various flow cytometric analysis software including DIVA, FlowJo, FCS express, and GraphPad is highly desirable..
Education • Bachelor's Degree or equivalent education with typically 0-3 years of experience, or Master's Degree or equivalent education with typically zero - two years of experience
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