Research Associate at University of North Carolina at Chapel Hill in chapel hill, North Carolina

Job Description:

Department:

SOP-SGC Ctr for Chem Biology-452102

Career Area :

Research Professionals

Posting Open Date:

12/12/2024

Application Deadline:

01/02/2025

Open Until Filled:

No

Position Type:

Permanent Staff (EHRA NF)

Working Title:

Research Associate

Appointment Type:

EHRA Non-Faculty

Position Number:

20068428

Vacancy ID:

NF0008729

Full Time/Part Time:

Full-Time Permanent

FTE:

1

Hours per week:

40

Position Location:

North Carolina, US

Hiring Range:

$55,100 - $65,000

Proposed Start Date:

03/03/2025

Be a Tar Heel!:

A global higher education leader in innovative teaching, research and public service, the
University of North Carolina at Chapel Hill consistently ranks as
one of the nation's top public universities. Known for its beautiful campus, world-class medical care, commitment to the arts and top athletic programs, Carolina is an ideal place to teach, work and learn.One of the best college towns and best places to live in the United States, Chapel Hill has diverse social, cultural, recreation and professional opportunities that span the campus and community.University employees can choose from a wide range of
professional training opportunities for career growth, skill development and lifelong learning and enjoy
exclusive perks for numerous retail, restaurant and performing arts discounts, savings on local child care centers and special rates on select campus events. UNC-Chapel Hill offers full-time employees a
comprehensive benefits package, paid leave, and a variety of health, life and retirement plans and additional programs that support a healthy work/life balance.

Primary Purpose of Organizational Unit:

The UNC Eshelman School of Pharmacy (www.pharmacy.unc.edu) is one of six health science schools (Pharmacy, Nursing, Dentistry, Social Work, Public Health, Medicine) at the University of North Carolina at Chapel Hill and is one of the oldest health science academic programs at Chapel Hill. The School teaches approximately 600 PharmD students and 145 graduate students. The School has built a reputation for its continued pursuit of excellence, rigorous education and training programs, cutting-edge multidisciplinary research, progressive pharmacy practices, efficient business operations, and its outstanding faculty, staff, and students. The School was named the number one School of Pharmacy in the U.S. by the U.S. News and World Report. The School has experienced unprecedented growth and success and continues to strategically position itself for sustained impact, as articulated in the School's Strategic Plan (https://pharmacy.unc.edu/about/oe/strategic-plan/).


Our Vision is to be the global leader in pharmacy and pharmaceutical sciences. Our Mission is to prepare leaders and innovators to solve the world's most pressing health care challenges. We are Advancing Medicine for Life through innovation and collaboration in pharmacy practice, education, research, and public service.

Position Summary:

The Structural Genomics Consortium Center for Chemical Biology in the UNC Eshelman School of Pharmacy is a multi-disciplinary research group that uses cell biology, chemical biology, and medicinal chemistry to generate open science research tools and data for the dark proteome.


We are seeking a highly self-motivated and experienced research associate to support key medicinal chemistry capabilities at the SGC-UNC. The person hired will join SGC-UNC and support collaborative drug discovery projects and the investigation of proteins implicated in disease, especially those that have been historically understudied. This position is responsible for providing synthetic and drug development support, including the measurement of physicochemical properties and pharmacokinetic analyses, and interfacing with the cell biology team as part of iterative optimization efforts. The applicant must have expertise in organic chemistry, medicinal chemistry, and interpretation of biological assay and pharmacokinetic study results. The successful applicant will be familiar with and capable of performing a wide range of lab procedures, including running chemical reactions, isolation and purification of products, use of microwave reactors and automated purification and analytical instrumentation, interpretation of analytical spectra, and other standard laboratory practices such as TLC and LC-MS. The applicant must be able to prepare presentations and manuscripts as well as demonstrate a high level of attention to detail and quality. The research associate will function as part of a multidisciplinary team, which requires he/she to be a strong team player, and have excellent written and verbal communication skills. The hired individual is also expected to take on some lab organization and maintenance responsibilities, including but not limited to maintaining reagents, maintaining databases, and general maintenance and upkeep of laboratory space.

Minimum Education and Experience Requirements:

Relevant post-Baccalaureate degree required (or foreign degree equivalent); for candidates demonstrating comparable independent research productivity, will accept a relevant Bachelor's degree (or foreign degree equivalent) and 3 or more years of relevant experience in substitution. May require terminal degree and licensure.

Required Qualifications, Competencies, and Experience:

* Relevant post-baccalaureate degree required (or foreign degree equivalent)
* Experience with standard organic chemistry techniques
* Experience with hit to lead optimization
* Experience with automated purification and analytical instrumentation
* Experience with the execution and interpretation of physicochemical and pharmacokinetic experiments
* Experience with the interpretation of biological assay data
* Experience working in a research laboratory
* Ability to work as part of a multidisciplinary team
* Excellent organizational skills and attention to detail
* Strong written and verbal communication skills

Preferred Qualifications, Competencies, and Experience:

* Experience with manuscript preparation and submission
* Understanding of BBB penetrance and how to optimize molecules to enter the brain
* Familiarity with chemical probes

Special Physical/Mental Requirements:

* Must be able to lift up to 25 pounds with or without reasonable accommodation
* Work will include reaching and standing to adjust equipment as needed.

Campus Security Authority Responsibilities:

Not Applicable.

Special Instructions:

Apply online at
https://unc.peopleadmin.com/postings/292788
, with a CV/resume, and a list of at least 3 professional references with their full contact information. A cover letter is optional.

Apply Now