Scientist at Pacer Group in South San Francisco, California

Posted in Other 3 days ago.

Type: full-time





Job Description:

Job Title: Bio-conjugation Scientist

Duration: 12 Months (Possibility of extension)

Location: South San Francisco, CA 94080

Shift Hours: M-F 8:00 AM to 5:00 PM

Education Requirement:
• Minimum qualifications include a B.S./M.S/ PHD in chemistry, biochemistry, or related field, with industrial or academic experience.

Experience and Skills Required:
• Hands on experience with conjugation, purification and characterization of antibody drug conjugates, and experience using analytical techniques/instrumentation, including chromatographic techniques such as HIC (Hydrophobic Interaction Chromatography) and RP (Reverse Phase), SEC, SDS-PAGE, UV?Vis.

• Nice to have skills: Biologics analytic experience, purification techniques.

• Must have: Bio-conjugation experience, protein biochemistry and Chemistry background.

• Personality: Team player, Adheres to timeline, Communicative and collaborative.

Note: Onsite, 100% Lab based role.

Responsibilities:

Client is currently seeking highly motivated and exceptional a Bio-conjugation Scientist for positions within the Discovery Chemistry Department located at our South San Francisco, CA site.
• The successful candidate will join multidisciplinary, highly collaborative discovery teams to invent novel medicines by applying optimized conjugation protocols, analytical techniques, and data analysis to synthesize drug candidates and intermediates.
• Successful candidates must have excellent interpersonal, collaboration, and communication skills in a team environment.
• Additionally, it is expected that the successful candidate will learn quickly through on-the-job training to become increasingly skilled and independent in reaction setup, route design and optimization.

Specific responsibilities will include:
• Perform bioconjugations of linker-payload combinations to antibodies with emphasis on in-house established methods
• Selection and application of appropriate purification techniques for biologics (i.e., SEC, hydrophobic interaction chromatography, ion exchange chromatography)
• Acquisition and interpretation of analytical data such as LC/MS.

Notes:

Minimum 8 years of relevant industry experience is needed with BS/MS and 5 years with PHD. Required: Hands on experience with conjugation, purification and characterization of antibody drug conjugates, and experience using analytical techniques/instrumentation, including chromatographic techniques such as HIC (Hydrophobic Interaction Chromatography) and RP (Reverse Phase), SEC, SDS-PAGE, UV?Vis.
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